PSS Perfect Separation Solutions > Products > Chromatography Software > WinGPC UniChrom Data Evaluation

Ensure correct processing and benefit from technique-specific evaluations - WinGPC Data Evaluation

Add unparalleled functionality to your CDS with GPC/SEC calibration options

Flexible, feature-full and easy-to-use

  • Designed from ground-up for dealing with macromolecules and distributions
  • Convenient native data import options for many 3rd party CDS data
  • Compliant and validated, Compliance Pack for enhanced traceabilty and data integrity
  • Software Modules and Workflows for specific tasks
  • Upgrade paths to Workstation and Client/Server

WinGPC Key Features


WinGPC UniChrom Data Evaluation software can process data from the following sources:

Native data formats

  • Thermo Scientific™ Chromeleon™ 7.2 (and later versions)
  • Agilent Technologies ChemStation
  • Agilent Technologies EZ Chrom ASCII/CSV
  • Jasco MD-910
  • PSS legacy data
  • Hitachi D-7000 Software

International standards for analytical data interchange

  • Standard ASCII
  • AIA/AnDI/CDF Version 2

Supported Techniques

  • GPC (Gel Permeation Chromatography), SEC (Size Exclusion Chromatography), GFC (Gel Filtration Chromatography) - all concentration detectors
  • GPC/SEC/GFC Multi Detection with concentration detectors
  • HPLC Quantification
  • HDC (Hydrodynamic Chromatography)
  • Interaction Polymer Chromatography (IPC)
  • SEC-Gradient
  • 2D-Chromatography
    • Offline 2D

Calibration Options

  • Narrow standard calibration
  • Broad standard calibration (sevaral including broad on narrow)
  • Integral/Cumulative match calibration
  • Universal calibration using Mark-Houwink coefficients
  • Detector calibration for concentration determination/HPLC Quantification
  • Radii calibration
  • Heparin End Group calibration
  • Dextran EP/USP calibration


ReportDesigner Create your own layouts with your choice of content and style.
Compliance Pack Enables to meet the requirements for GAMP, GxP, ICH, and FDA 21 CFR part 11.
Heparin/End group Adds determination of the functionality distribution and end-group-based calibration e.g. for LMWH (low molecular weight heparin based on EP).

Learn More


What does MCDS mean? Is WinGPC Compliant? How do users rate WinGPC? Learn more in this video.


Validated software and traceable results in an easy-to-use software.


Present results using standard or customized layouts and export data and results. 

Chromeleon Import

Connect to the Chromeleon Data Vault to evaluate WinGPC.

FAQ - Frequently Asked Questions

Browse through our FAQs to find out more.

  • Scope
  • Features
  • Data Integrity
  • Updates/Upgrades
  • Services

With which instruments can I use WinGPC?
Data capture can be accomplished with almost every analysis instrument from any vendor. The only prerequisite is the presence of analog signal outputs at each device.

For various instruments it is also possible to control them. Besides the PSS instruments the following manufacturers and models are supported:

  • Agilent LC 1100/1120/1200/1220/1260/1290
  • Thermo/Dionex UHPLC+, UltiMate
  • Shimadzu Nexera, LC-2010/20A/10A/8A LC
  • Shodex RI10x/20x
  • Tosoh EcoSEC
  • Waters

Do I need to have access to the internet to run WinGPC?
No, after installation WinGPC comprises all functions to acquire and analyse data. The WinGPC database has been specifically developed for WinGPC, registration of each single installation is NOT rerquired.

Is WinGPC limited to GPC/SEC related work?
No, WinGPC is a multi-method CDS with focus on macromolecular characterization. It covers all techniques for in-depth characterization of natural and synthetic  bio(polymers) and proteins.

We have multiple instruments which we want to operate with a single software solution. Can WinGPC handle mutiple instruments?
Yes, this was on the design specs from day one. You can operate WinGPC in a workstation installation with up to 4 instruments from different (or the same) vendors. Networked installations can operate up to 4 instruments per license and a client/Server installation can handle even more with just a single installation on a centralized server.

Which functionalities are present in WinGPC without any software modules?
WinGPC functionality includes data acquisition, data storage in the WinGPC data base, access to the column database, automated and interactive data analysis including system performance tests, HPLC and Multi area analysis, software wizards, calibration (narrow, broad, cumulative match, universal calibration based on Mark-Houwink coefficients, Dextran EP/USP), result calculation including result uncertainty and standard reporting.

Which possibilities for automated data capture and analysis are given in WinGPC?
Quick analysis provides batch processing including atuomated calibration.

Which tools help unexperienced users to operate WinGPC?
Novice users can use the WinGPC wizards. Those will guide you step-by-step through specific tasks. WinGPC videos and the quick reference guides offer on-demand support.

Can I use WinGPC to measure the quality of my signals and system? Can I assess the precision of my GPC results with WinGPC?
WinGPC offers comprehensive system performance tests meeting the requirements of national and international standards. Based on signal quality, calibration quality and system stability WinGPC determines the result uncertainty for all results.

Is WinGPC fully compliant to FDA 21CFR11 and ISO9001?
The optional Compliance Pack adds all functionality to allow for full compliance with 21CFR part 11 and GxP.

Is it possible to control access to WinGPC for selected users?
Access can be limited to selected users when the Compliance Pack is licensed. In non-regulated environments WinGPC use can be password-protected.

Are there different user levels given in WinGPC?
The Compliance Pack provides 4 levels (administrator, advanced user, user, guest). WinGPC comes with recommended privileges for each level, but of course the selection can be adapted to each organization's needs.

How does WinGPC ensure that no data can get lost?
All WinGPC data are stored in the propriatery WinGPC database. Each injection is automatically documented with it's date and time stamp.

How does WinGPC prevent manipulation of data and results?
All WinGPC data (raw data, meta data, calibration data etc.) are stored in the WinGPC data base. Data are encrypted and saved in projects comprising several data files. Raw data can never be manipulated, as all operations (inter detector delay correction, (optional) flow-correction, analysis etc.) are perfomed with a copy of the raw data.

What is the current WinGPC version?
PSS WinGPC UniChrom 8.3 SR3, Build number: 9050 (released: September 2019)
Updates to WinGPC UniChrom are available, contact us for a quote.


Which kind of support is offered by PSS for WinGPC?
The PSS software team offers comprehensive support. Your contact is not only a WinGPC expert, but also trained in macromolecular chemistry and physics and will organize inhouse support from other PSS departments such as the column department or the contract analysis department.
PSS uses TeamViewer for online support. For those organizations where IT does not allow that the WinGPC database concept allows for easy exchange of information to answer questions efficiently. 
PSS offers also preferred software support contracts with guaranteed reaction times.  

The WinGPC Newsletter (4 editions per year) offers Tips&Tricks and Application notes. You can sign-up here to receive information.

Is it possible to perform an installation qualification (IQ) and/or an operational qualification (OQ) of WinGPC?
PSS offers Software IQ/OQ as a service. Just contact us to discuss your needs.

keyboard_arrow_down keyboard_arrow_up

Die Webseite ist für moderne Browser optimiert. In Ihrem Browser können Inhalte fehlerhaft angezeigt werden.