One Software for Liquid Chromatography of (Bio)Polymers and Proteins - WinGPC MCDS

Macromolecular Chromatography Data System for GPC/SEC/GFC, IPC and 2D

Flexible, feature-full and easy-to-use

  • Designed from ground-up for dealing with heterogeneity of macromolecules and distributions
  • Unparalleled functionality and calibration options for GPC/SEC/GFC, Interaction Polymer Chromatography and 2-dimensional Chromatography
  • Compliant and validated, Compliance Pack for enhanced traceability and data integrity
  • Read and process data from all sources:
    • (3rd party) ChromPilot Acquisition and Control for > 300 different LC modules and specialty GPC/SEC detectors
    • for all: 3rd Party Data Acquisition with PSS Interfaces
    • Data import options for CDS data and standard data protocols
  • Software Modules and Workflows for specific tasks
  • Scalable software offering 3rd party CDS data reprocessing, single workstation and networked systems up to Client/Server operation

WinGPC UniChrom
Data Evaluation

Process existing LC CDS data to allow for precise and accurate GPC/SEC/GFC data processing with all calibration options. 

WinGPC UniChrom MultiWorkstation
Acquire and process data in a local or a network environment. All software modules supported, for up to 4 instruments per single license.

WinGPC UniChrom

Ease administration, allow flexible user access and operation and protect your data. All software modules supported, for multiple instruments and users.

Current WinGPC Version

  • Current Version and Updates
  • PC Requirements
  • Test your system

WinGPC Data Evaluation/MultiWorkstation

PSS WinGPC UniChrom 8.4 Build number: 9666 July 2021

Update options:

  • Software update from previous WinGPC UniChrom release (P/N 400-0210)
  • Software update from WinGPC Unity (P/N 400-0209)
  • Software update from WinGPC 6.x or 7.x (P/N 400-0208)
  • Software update from Atari, WinGPC 3.x or 4.x (P/N 400-0207)


WinGPC Client/Server

PSS WinGPC UniChrom 8.3 Service Release 3 Build number: 9330 March 2020

Update options:

  • Software update for WinGPC Client/Server 

WinGPC Data Evaluation and MultiWorkstation

IBM compatible computer with quad core processor, 2 GHz or better (3 GHz for MS module)
8 GB or more (12 GB for MS module) 80 GB for single instruments, 200 GB for multi instrument configurations,
2 USB drives for setup and dongle,
Monitor 19" minimum, 1280x1024 minimum, 16 bit colors minimum, keyboard, mouse and hard drive.

Operating Systems

  • Windows 10: (not Mobile and Home) (32 and 64 bit)
  • Windows 8: all editions but not RT  (32 and 64 bit)
  • Windows 7: all editions but Starter and Home (32 and 64 bit), incl. SP1

For ChromPilot and Compliance Pack Intallations: .Net Framework 3.5 SP1 and 4.5.x required

WinGPC Client/Server

Server with dual Intel Xeon quad-core processor, 2.4 GHz or better (depending on number of concurrent users / controlled systems)
24 GB RAM or more (depending on number of concurrent users / controlled systems)
60 GB drives for multi instrument configurations; USB drive for setup
additional storage for data, user/column/sample databases depending on data volume

Operating Systems   

  • Windows 2008 Server, Windows 2008 R2 Server,
  • Windows 2012 Server, Windows 2012 R2 Server,
  • Windows 2016 Server

Microsoft Remote Desktop Services (RDS) enabled

For ChromPilot and Compliance Pack Intallations: .Net Framework 3.5 SP1 and 4.5.x required

Is your PC ready for the current WinGPC version?

SystemCheck Utility will tell you that for all MultiWorkstation and Data Evaluation WinGPC versions.

The PSS SystemCheck Utility allows to check if a target computer will be fit for purpose (pre-install site preparation test) and generates a list of potential conflicts or problems with a future PSS software installation on that target PC.

SystemCheck Utility Documentation.

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Discover More about WinGPC

Acquire Data or Import Files

Stay flexible and protect your investments: WinGPC supports control for all major LC brands and import of data files.

Data Analysis and Software Modules

Get the most out of your data: comprehensive data evaluation and powerful software modules.

Reporting and Data/Result Export

Present results in customized or standards layouts and export data and results. 

Compliance and Data Integrity

Validated and compliant and easy-to-use and flexible? See how WinGPC handles this.


What does MCDS mean? Is WinGPC Compliant? How do users rate WinGPC? Learn more in this video.

WinGPC Case Studies

Case study with typical WinGPC installations. What are the most useful features? Request your free pdf.


Demo at Your Desk

Talk to one of our experts and discover more! Contat us to arrange a WinGPC Live Demo.

FAQ - Frequently Asked Questions

Browse through our FAQs to find out more.

  • Scope
  • Features
  • Data Integrity
  • Updates/Upgrades
  • Services

With which instruments can I use WinGPC?
Data capture can be accomplished with almost every analysis instrument from any vendor. The only prerequisite is the presence of analog signal outputs at each device.

For various instruments it is also possible to control them. Besides the PSS instruments the following manufacturers and models are supported:

  • Agilent LC 1100/1120/1200/1220/1260/1290
  • Thermo/Dionex UHPLC+, UltiMate
  • Shimadzu Nexera, LC40, i-Series, LC-2010/20A/10A/8A LC
  • Shodex RI10x/20x
  • Tosoh EcoSEC
  • Waters APC

Do I need to have access to the internet to run WinGPC?
No, after installation WinGPC comprises all functions to acquire and analyse data. The WinGPC database has been specifically developed for WinGPC, registration of each single installation is NOT rerquired.

Is WinGPC limited to GPC/SEC related work?
No, WinGPC is a multi-method CDS with focus on macromolecular characterization. It covers all techniques for in-depth characterization of natural and synthetic  bio(polymers) and proteins.

We have multiple instruments which we want to operate with a single software solution. Can WinGPC handle mutiple instruments?
Yes, this was on the design specs from day one. You can operate WinGPC in a workstation installation with up to 4 instruments from different (or the same) vendors. Networked installations can operate up to 4 instruments per license and a client/Server installation can handle even more with just a single installation on a centralized server.

Which functionalities are present in WinGPC without any software modules?
WinGPC functionality includes data acquisition, data storage in the WinGPC data base, access to the column database, automated and interactive data analysis including system performance tests, HPLC and Multi area analysis, software wizards, calibration (narrow, broad, cumulative match, universal calibration based on Mark-Houwink coefficients, Dextran EP/USP), result calculation including result uncertainty and standard reporting.

Which possibilities for automated data capture and analysis are given in WinGPC?
Quick analysis provides batch processing including atuomated calibration.

Which tools help unexperienced users to operate WinGPC?
Novice users can use the WinGPC wizards. Those will guide you step-by-step through specific tasks. WinGPC videos and the quick reference guides offer on-demand support.

Can I use WinGPC to measure the quality of my signals and system? Can I assess the precision of my GPC results with WinGPC?
WinGPC offers comprehensive system performance tests meeting the requirements of national and international standards. Based on signal quality, calibration quality and system stability WinGPC determines the result uncertainty for all results.

Is WinGPC fully compliant to FDA 21CFR11 and ISO9001?
The optional Compliance Pack adds all functionality to allow for full compliance with 21CFR part 11 and GxP.

Is it possible to control access to WinGPC for selected users?
Access can be limited to selected users when the Compliance Pack is licensed. In non-regulated environments WinGPC use can be password-protected.

Are there different user levels given in WinGPC?
The Compliance Pack provides 4 levels (administrator, advanced user, user, guest). WinGPC comes with recommended privileges for each level, but of course the selection can be adapted to each organization's needs.

How does WinGPC ensure that no data can get lost?
All WinGPC data are stored in the propriatery WinGPC database. Each injection is automatically documented with it's date and time stamp.

How does WinGPC prevent manipulation of data and results?
All WinGPC data (raw data, meta data, calibration data etc.) are stored in the WinGPC data base. Data are encrypted and saved in projects comprising several data files. Raw data can never be manipulated, as all operations (inter detector delay correction, (optional) flow-correction, analysis etc.) are perfomed with a copy of the raw data.

What is the current WinGPC version?
PSS WinGPC UniChrom 8.4 Build number: 9666 (released: July 2021)
Updates to WinGPC UniChrom are available, contact us for a quote.


Which kind of support is offered by PSS for WinGPC?
The PSS software team offers comprehensive support. Your contact is not only a WinGPC expert, but also trained in macromolecular chemistry and physics and will organize inhouse support from other PSS departments such as the column department or the contract analysis department.
PSS uses TeamViewer for online support. For those organizations where IT does not allow that the WinGPC database concept allows for easy exchange of information to answer questions efficiently. 
PSS offers also preferred software support contracts with guaranteed reaction times. 
The WinGPC Newsletter (4 editions per year) offers Tips&Tricks and Application notes. You can sign-up here to receive information.

Is it possible to perform an installation qualification (IQ) and/or an operational qualification (OQ) of WinGPC?
PSS offers Software IQ/OQ as a service. Just contact us to discuss your needs.

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