PSS Perfect Separation Solutions > Products > Chromatography Software > WinGPC UniChrom MCDS > Applicability
- Conventional GPC (Gel Permeation Chromatography), SEC (Size Exclusion Chromatography), GFC (Gel Filtration Chromatography)
- GPC/SEC/GFC-Light Scattering Detection (static, dynamic) (1-angle, multi angle)
- GPC/SEC/GFC-Viscometry
- GPC/SEC/GFC-Triple Detection
- GPC/SEC/GFC-FTIR hyphenation
- GPC/SEC/GFC-Mass Spectrometry hyphenation
- GPC/SEC/GFC Dual Detection
- HPLC Quantification
- CE Quantification
- SFC Quantification
- HDC (Hydrodynamic Chromatography)
- Interaction Polymer Chromatography (IPC)
- Isocratic/Gradient Chromatography
- Chromatography under Critical Conditions
- Chromatography under Limiting Conditions
- SEC-Gradient
- Temperature Gradient Interaction Chromatography (TGIC)
- Temperature Rising Elution Fractionation (TREF)
- 2D-Chromatography (HPLC/IPC, GPC/SEC/GFC, TGIC/TREF, IC, CE, GC, FFF)
- Heart-Cutting 2D
- Multiple Heart-Cutting 2D
- Automated fraction collection/re-injection 2D
- Comprenhensive online 2D
- Offline 2D
- GPC (Gel Permeation Chromatography), SEC (Size Exclusion Chromatography), GFC (Gel Filtration Chromatography) - all concentration detectors
- GPC/SEC/GFC Multi Detection with concentration detectors
- HPLC Quantification
- HDC (Hydrodynamic Chromatography)
- Interaction Polymer Chromatography (IPC)
- SEC-Gradient
- 2D-Chromatography
- Offline 2D
- Narrow standard calibration
- Broad standard calibration (sevaral including broad on narrow)
- Integral/Cumulative match calibration
- Universal calibration (GPC/SEC/GFC-Viscometry) (requires Viscometry module)
- Light scattering calibration (GPC/SEC/GFC-LS) (requires LS or MALLS module)
- Universal calibration using Mark-Houwink coefficients
- Detector calibration for concentration determination/HPLC Quantification
- Radii calibration
- Heparin End Group calibration (requires Heparin/End group module)
- Dextran EP/USP calibration
- Mass Spectrometry calibration (requires Mass Spectrometry module)
- Chemical Heterogeneity (based on composition standards, requires Chemical Heterogeneity module)
- Copolymer Composition (based on dual detection, requires Copolymer module)
- Narrow standard calibration
- Broad standard calibration (sevaral including broad on narrow)
- Integral/Cumulative match calibration
- Universal calibration using Mark-Houwink coefficients
- Detector calibration for concentration determination/HPLC Quantification
- Radii calibration
- Heparin End Group calibration
- Dextran EP/USP calibration
Multi instrument control | Adds additional time bases to WinGPC. One WinGPC License can acquire data from up to four instruments. |
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Compliance Pack | Enables to meet the requirements for GAMP, GxP, ICH, and FDA 21 CFR part 11. |
3D Spectra | Adds omprehensive analysis and presentation of 3D-data fields for PDA/DAD or Fluorescence detectors. |
Light scattering modules | 2 separate Modules for Single Angle (RALS/RALLS, LALS/LALLS) and Multi Angle (MALS/MALLS) Light Scattering. Both modules include static and dynamic light scattering. |
Viscosity | Adds universal calibration option, viscosity results and Mark-Houwink Plots. Includes Triple detection option when a light scattering module is present. |
Heparin/End group | Adds determination of the functionality distribution and end-group-based calibration e.g. for LMWH (low molecular weight heparin based on EP). |
Copolymer Analysis | Adds determination of the comonomer distribution and copolymer calibration based on composition. |
Chemical Heterogeneity | Adds determination of the average chemical composition, skew and width of the compositional distribution as well as calibration based on composition standards. |
2D Chromatography | Combines the separation power of two different chromatographic methods (dimensions), supports offline, heart-cut and comprehensive online 2D. Allows for calibration of both dimensions to measure e.g. chemical composition and molar mass distribution simultaneously. |
Mass Spectrometry | Adds data import of masss spectrometry files from ChemStation, MassHunter, Xcalibur and MassLynx with automatic assignement of degree of charge, degree of polymerization and the molar mass of the end group. Allows to create MS based calibration curves to determine true molar masses. |
ReportDesigner | Create your own layouts with your choice of content and style. |
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Compliance Pack | Enables to meet the requirements for GAMP, GxP, ICH, and FDA 21 CFR part 11. |
Heparin/End group | Adds determination of the functionality distribution and end-group-based calibration e.g. for LMWH (low molecular weight heparin based on EP). |
WinGPC UniChrom Data Evaluation software can process data from the following sources:
Native data formats
- Thermo Scientific™ Chromeleon™ 7.2 (and later versions)
- Agilent Technologies ChemStation
- Agilent Technologies EZ Chrom ASCII/CSV
- Jasco MD-910
- PSS legacy data
- Hitachi D-7000 Software
International standards for analytical data interchange
- Standard ASCII
- AIA/AnDI/CDF Version 2