USP Column Recommendations

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USP Column Recommendation

The United States Pharmacopeia (USP) is a standard source for many pharmaceutical methods and it specifies columns by packing materials rather than by manufacturer.

Find below a list of the recommended PSS columns suitable for methods listed with the USP.

USP No	USP Description	Matching PSS Material
L20	Dihydroxypropane groups chemically bonded to porous silica particles, 3 to 10µm in diameter.	PROTEEMA
L21	A rigid, spherical styrene-divinylbenzene copolymer, 5 to 10 µm in diameter.	SDV
L22	A cation group resin made of porous polystyrene gel with sulfonic acid groups, about 10 µm in size.	MCX
L23	An ion exchange resin made of porous polymethacrylate or polyacrylate gel with quaternary ammonium groups, about 10 µm in size.	NOVEMA Max
L25	Packing having the capacity to separate compounds with a MW range from 100 to 5 000 Da (as determined by polyethylene oxide), applied to neutral, anionic and cationic water-soluble polymers.	SUPREMA (100 Å)
L33	Packing having the capacity to separate proteins by molecular size over a range of 4 000 to 400 000 Da. It is spherical, silica-based, and processed to provide pH stability.	PROTEEMA (300 Å)
L37	Polymethacrylate gel packing having the capacity to separate proteins by molecular size over a range of 2 000 – 40 000 Da MW.	SUPREMA (30 Å)
L38	Methacrylate-based size exclusion packing for water-solubles.	SUPREMA
L39	Hydrophilic polyhydroxymethacrylate gel of totally porous spherical resin	SUPREMA
L59	Packing having the capacity to separate proteins by molecular weight over the range of 5 to 7 000 kDa. It is spherical (5 - 10µm), silica-based, and processed to provide hydrophilic characteristics and pH stability.	PROTEEMA (300 Å)