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Need help finding the right GPC/SEC Columns? Try our GPC/SEC Column Selector Tool
Column choice in SEC depends on column resolving range, identified by calibration with standards appropriate to analyte type, molecular weight range, and size in solution.
- Publication Part Number: 5991-2463EN
- Created: 14 May 2013
- 117 KB
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GPC/SEC analysis of gelatin in an aqueous phosphate buffer solution using Agilent PROTEEMA columns.
- Publication Part Number: 5994-6270EN
- Created: 01 Aug 2023
- 1 MB
GPC/SEC analysis of human insulin in water/acetic acid/acetonitrile/L-Arginin using Agilent PROTEEMA columns.
- Publication Part Number: 5994-6259EN
- Created: 01 Aug 2023
- 1 MB
GPC/SEC analysis of gelatin in an aqueous phosphate buffer solution using Agilent PROTEEMA columns.
- Publication Part Number: 5994-6269EN
- Created: 01 Aug 2023
- 2 MB
GPC/SEC analysis of low molecular weight heparin in an aqueous phosphate buffer solution using Agilent PROTEEMA columns according to EU pharmacopeia.
- Publication Part Number: 5994-6319EN
- Created: 01 July 2023
- 1 MB
This application brief describes the GPC/SEC analysis of monoclonal antibodies (mAb) to determine the content and size of aggregates and fragments.
- Publication Part Number: 5994-5721EN
- Created: 02 Mar 2023
- 223 KB
This application brief illustrates the GPC/SEC analysis of proteins from low to medium molecular weight using an Agilent PROTEEMA column.
- Publication Part Number: 5994-5727EN
- Created: 02 Mar 2023
- 155 KB
This application brief illustrates the GPC/SEC analysis of proteins from medium to high molecular weight using an Agilent PROTEEMA column.
- Publication Part Number: 5994-5728EN
- Created: 02 Mar 2023
- 152 KB
Methods are given for the use of Agilent Bio-SEC columns, with LS, UV and RI detection, for quantification or quality control of protein aggregates
- Publication Part Number: 5991-1400EN
- Created: 07 Jan 2013
- 284 KB
Publication Part Number | 5991-1400EN | ||||
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A mixture of standard proteins was used to determine the resolution characteristics of the columns...
- Publication Part Number: 5990-8895EN
- Created: 13 Sep 2011
- 703 KB
Publication Part Number | 5990-8895EN | ||||
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The aggregation of protein therapeutics has become a major concern for the
- Publication Part Number: 5990-8613EN
- Created: 02 Aug 2011
- 602 KB
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Application note for the characterization of monoclonal antibodies on the Agilent 1260 Infinity Bio-inert Quaternary LC by SEC using the Agilent BioSEC columns
- Publication Part Number: 5990-6414EN
- Created: 01 Feb 2011
- 996 KB
Publication Part Number | 5990-6414EN | ||||
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The enzyme l-asparaginase poses a challenge for quantifying aggregation as its structure may produce high molecular weight aggregates.
- Publication Part Number: 5994-6587EN
- Created: 28 July 2023
- 543 KB
This collection of 10 Agilent ‘aggregate and fragment analysis’ app notes also includes our guide on how to perform SEC for biomolecule analysis.
- Publication Part Number: 5994-0032EN
- Created: 01 Apr 2021
- 7 MB